Prolactin rescues and primes autoreactive B cells directly and indirectly through dendritic cells in B6.Sle3mice
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چکیده
منابع مشابه
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Peripheral tolerance is crucial for avoiding activation of self-reactive T cells to tissue-restricted antigens. Sterile tissue injury can break peripheral tolerance, but it is unclear how autoreactive T cells get activated in response to self. An example of a sterile injury is myocardial infarction (MI). We hypothesized that tissue necrosis is an activator of dendritic cells (DCs), which contro...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2013
ISSN: 0009-9104
DOI: 10.1111/cei.12050